Optimization of Management in Patients With Cardiovascular Disease After Lower Limb Joint Replacement

Recruiting

• Conditions: Thromboembolism; Anticoagulant-induced Bleeding
• Interventions: Other: No intervention

• Registration Number: NCT06627933
• Lead Sponsor: I.M. Sechenov First Moscow State Medical University

Brief Summary

The goal of the study is to evaluate the frequency of cardiovascular and thromboembolic complications in patients with cardiovascular disease after lower limb joint replacement, the influence of known risk factors and strategies for perioperative prevention of thromboembolic complications on the frequency of cardiovascular complications and to develop approaches to optimize antithrombotic prevention tactics.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-15
• Status Verified: 2024-10
• Study First Submitted: 2024-10-03
• Study First Submitted QC: 2024-10-03
• Study First Posted: 2024-10-04
• Last Update Submitted: 2024-10-07
• Last Update Posted: 2024-10-09
• Primary Completion: 2025-01-15
• Study Completion: 2027-01-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Informed consent
• Age older than 18 y.o.
• Cardiovascular disease
• Indications for planned lower limb joint replacement surgery

Exclusion Criteria

• Pregnancy
• Psychiatric disorders
• Decompensated heart failure or acute heart failure
• Known diagnosis of cancer

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
High thromboembolic risk	No intervention	-

Primary Outcome Measures

Name	Time	Method
Bleeding	6 months	All the cases of major and minor bleeding within 6 months
Thromboembolism	6 months	All the cases of venous thromboembolism within 6 months

Trial Locations

Locations (1)

University Hospital #1; 🇷🇺 Moscow, Russian Federation