Cognitive decline in cancer: A cross-sectional study

Not Applicable

Recruiting

Conditions: cancer
cancer-related cognitive impairment (CRCI)
cancer psychosocial distress
neurodegenerative disorders
Neurological - Neurodegenerative diseases
Cancer - Any cancer

Registration Number: ACTRN12622001537741

Lead Sponsor: Curtin University

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 200

Inclusion Criteria

Study inclusion criteria require participants to be aged over 18 years old, currently live in Perth and Peel regions of Western Australia (or close enough), have been diagnosed with non-CNS cancer, be currently undergoing any treatment, and have a working proficiency of the English language.

To provide a comparative baseline across assessments, 20-25% of the sample will consist of healthy controls that meet all other inclusion/exclusion criteria but are cancer-naive and are not undergoing treatment.

Exclusion Criteria

Exclusion criteria preclude participation of individuals with premorbid developmental / cognitive dysfunction; premorbid neurodegenerative conditions; pregnancy; and central nervous system metastases.

Enrolment in other trials may be an exclusion criterion - case by case basis.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Verbal memory, as assessed by the Hopkins Verbal Learning Test-Revised (HVLT-R).[ Baseline.];Peripheral BDNF levels, as measured by plasma assays.[ Baseline.];Attention / executive functioning, as assessed by the Trail Making Test (TMT).[ Baseline.]

Secondary Outcome Measures