to study whether local endometrial biopsy before ivf improves pregnancy rates in repeated failure cases
Not Applicable
- Conditions
- Health Condition 1: null- patient undergoing repeat ivf cycles, with failed previous ivf cycles
- Registration Number
- CTRI/2013/04/003564
- Lead Sponsor
- CHRISTIAN MEDICAL COLLEGE
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 180
Inclusion Criteria
Inclusion criteria.
Age -38 or less
FSH < 10
BMI between 20 â?? 29.kg/m2
1 previous failed IVF when at least two Grade 1 embryos were transferred.
Suspected implantation failure.
Exclusion Criteria
Exclusion Criteria:Poor responders â?? less than 4 oocytes in a previous IVF cycle
Local uterine pathology â?? adhesions / polyp ect.
Endometriosis / Adenomyosis
Uterine malformations
Systemic disease â?? like Diabetes / SLE.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical pregnancy rate: number of clinical pregnancies (ultrasound confirmed)at 6wks expressed per embryo transfer. <br/ ><br>Miscarriage: Delivery occurring prior to 20 weeks gestation. <br/ ><br>implantation rate: no of embryos transferred to number of gestation sacs in transvaginal scan at 6 weeks <br/ ><br>Timepoint: 6 weeks of gestation by transvaginal scan
- Secondary Outcome Measures
Name Time Method live birth rate, associated complications i.e pain ,bleedingTimepoint: delivery beyond 37 wks of gestation