Comparing the effect of probiotic and conventional yoghurt consumption in patients with non-alcoholic fatty liver disease (NAFLD)
- Conditions
- onalcoholic fatty liver disease (NAFLD).nonalcoholic steatohepatitis
- Registration Number
- IRCT201210313664N8
- Lead Sponsor
- Vice-chancellor for research-Tabriz University of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Patients who agree to participate in the study
; Women aged 20-50 years (premenopausal) and in men 20-65 years; BMI range between 25 to 40 kg/ m2; suffering from Nonalcoholic fatty liver disease
Exclusion criteria: suffering from gastrointestinal disease; diabetes and rheumatoid arthritis; Receiving Antibiotics during the two weeks before the study and during the study; Follow the diet and weight loss; Receiving Supplements of vitamins, antioxidants, fiber and omega-3 within 3 weeks before baseline and during the study; presence of pregnancy or lactation or menopause; taking Contraceptive drugs; Liver transplantation; alcohol intake; any cause of chronic liver disease other than NAFLD such as testing positive for hepatitis B, hepatitis C and autoimmune hepatitis – Immune; History of cancer and treatment; performing a complete intravenous feeding; rapid weight loss; cut part of the intestine and Gastropathy; drugs such as corticosteroids, amiodarone, tamoxifen, cyclins, perhexiline, methotrexate, aspirin, and hydralazine;presence of inherited Hemochromatosis (transferrin saturation greater than 45%) and Wilson's disease; Cholestatic liver disease; advanced liver disease; heart failure; thyroid (abnormal TSH) and renal disease; gastric bypass surgery; cachexia
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Adiponectin. Timepoint: Baseline and at the end of intervention. Method of measurement: ELISA.
- Secondary Outcome Measures
Name Time Method