Evaluation of seizures in infants with moderate and severe asphyxia
Phase 1
- Conditions
- moderate and severe asphyxia.Birth asphyxia
- Registration Number
- IRCT20081021001378N14
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
term newborn with 37 week gestational age
more than 2 kg birth weight
pH less than 7
base deficit more than 12 mmol/lit
Exclusion Criteria
preterm infants
Anomalies
less than 2 kg birth weight
Genetic disorders
Neuromacular disorders
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The incidence of seizures. Timepoint: duration of hospitalization. Method of measurement: Based on clinical signs.;Time of start feeding. Timepoint: From the beginning of hospitalization to the end of hospitalization. Method of measurement: Based on abdominal examination, the presence of intestinal sounds and the absence of vomiting.;Feeding tolerance. Timepoint: From the beginning of feeding to the end of hospitalization. Method of measurement: Abdominal examination, clinical observation of the infant and evaluation for vomiting or malnutrition.
- Secondary Outcome Measures
Name Time Method Evaluation of heart disorder at the end of acetaminophen treatment. Timepoint: duration of hospitalization. Method of measurement: Based on clinical signs and then if there are echocardiographic symptoms.