Electroencephalography in the Neonate: Seizure Detectio

Not Applicable

Conditions: eonatal Seizures
Neonatal Seizures
Neurological - Other neurological disorders
Reproductive Health and Childbirth - Complications of newborn

Registration Number: ACTRN12623000639628

Lead Sponsor: Queensland Institute of Medical Research (QIMR) Berghofer

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot yet recruiting

Sex: All

Target Recruitment: 40

Inclusion Criteria

Infants eligible for inclusion are infants born > 35 weeks gestational age and are at risk of seizures, these include infants who have had a seizure, with hypoxic ischaemic encephalopathy (HIE), or have had abnormal movements, with a clinical concern for seizures.

Exclusion Criteria

Exclusion criteria will be if the neonatal electrodes are unable to be placed adequately for a recording (e.g. other interfering equipment) or if the prognosis is extremely poor and redirection to palliative care is imminent.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Validation of EEG annotation by a neonatal seizure detection algorithm will be assessed, by comparing these results to the gold standard visual interpretation by the human expert (2 Paediatric Neurologists).[ Cumulative data will be assessed at the conclusion of the data collection period.]

Secondary Outcome Measures

Name	Time	Method
To determine the accuracy of the seizure detection algorithm across different EEG acquisition machines (is accuracy similar between commercial grade EEG machine and a custom-built EEG machine)[ Cumulative data will be assessed at the conclusion of the data collection period.];Determine the applicability of the seizure detection algorithm i.e. visual assessment of the ability of the algorithm to run in real-time at the cotside.[ Cumulative data will be assessed at the conclusion of the data collection period.]