BREathprint Variation during Intubation, mechanical ventilation and Anesthesia.
Recruiting
- Conditions
- Ventilator associated lung injury
- Registration Number
- NL-OMON24277
- Lead Sponsor
- Academic Medical Center, Amsterdam
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 25
Inclusion Criteria
1. Planned elective surgery (with planned intubation >5h);
2. Informed consent;
Exclusion Criteria
1. < 18 years of age;
2. History of any chronic or acute pulmonary condition (asthma, COPD, CF, pulmonary malignancy or acute lung injury);
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Breathprint (exhaled biomarkers) as obtained by electronic nose measurement (Cyranose and ContiNose);<br /><br>2. Systemic biological markers of oxidative stress and lung injury (e.g. Urin acid, IL-1b, IL-6, IL-8, TNFa en MPO).
- Secondary Outcome Measures
Name Time Method