Organic mitral regurgitation (MR): genetic analysis, morphological and tissue characterization.

Recruiting

• Conditions: mitral valve prolapse; mitral valve regurgitation; 10046973; 10007510

• Registration Number: NL-OMON53095
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 300

Inclusion Criteria

patients > 18 years, referred to the LUMC for mitral valve repair for organic
mitral regurgitation

Exclusion Criteria

patiente with syndromal heart disease, mentally disable, active endocarditis

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Differences between Barlow and FED:<br /><br>- macroscopic: echocardiography<br /><br>- microscopic: mitral valve tissue analysis<br /><br>- familial distribution through pedigree analysis<br /><br>- genetic abnormalities through DNA analysis<br /><br><br /><br>See pages 16-19 of the Protocol</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>n/a</p><br>