Evaluating the effect of curcumin oral Gel on radiotherapy-induced mucositis
Phase 2
Completed
- Conditions
- oral mucositis (radiotherapy-induced mucositis).Other and unspecified lesions of oral mucosa
- Registration Number
- IRCT138904064255N1
- Lead Sponsor
- Tehran University of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 37
Inclusion Criteria
Patients older than 18 years, presence of head and neck cancer, minimum dose of radiation therapy 50 gy to induce mucositis, ability to use oral gel before radiotherapy session, signing informed consent
Exclusion criteria: suffering from any kind of oral disease such as active oral infection, ulcer, receiving chemotherapy combined with radiotherapy, inability to use oral gel
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Erythema. Timepoint: once a week during radiotherapy period. Method of measurement: milimeter.;Oral mucositis grade. Timepoint: once a week during radiotherapy period. Method of measurement: clinical examination.;Mouth burn. Timepoint: once a week during radiotherapy period. Method of measurement: visual analogue scale.;Oral ulcer. Timepoint: once a week during radiotherapy period. Method of measurement: clinical examination.
- Secondary Outcome Measures
Name Time Method Side effects. Timepoint: once a week during radiotherapy period. Method of measurement: asking the patient.