The Effect of Aerobic Interval Training on Obstructive Sleep Apnea

Not Applicable

Completed

• Conditions: Obstructive Sleep Apnea Syndrome
• Interventions: Behavioral: Aerobic Interval training; Behavioral: Control

• Registration Number: NCT01215617
• Lead Sponsor: Norwegian University of Science and Technology

Brief Summary

The purpose of this study is to investigate if 3 months of interval training improves obstructive sleep apnea in obese patients diagnosed with moderate to severe obstructive sleep apnea. The working hypothesis is that 3 months of 3 weekly aerobic interval training sessions improve obstructive sleep apnea and sleep quality in obese patients.

Detailed Description

Obstructive sleep apnea syndrome (OSAS) is characterized by repetitive obstruction and collapse of the upper airway resulting in successive episodes of cessation of or decreased respiratory airflow, causing oxygen desaturation, awakening, loud snoring and daytime sleepiness in patients. Sleep apnea is frequently associated with co-morbidity such as obesity, diabetes, hypertension, the metabolic syndrome and cardiovascular disease. Lack of exercise is associated with OSAS severity, independent of body mass. Participation and motivation to exercise is low in OSAS patients, with less that one third of the patients reporting regular exercise routines. We aim to investigate if aerobic interval training improves OSAS in obese subjects.

Study Timeline

• Study Start: 2010-10
• Study First Submitted: 2010-10-04
• Study First Submitted QC: 2010-10-05
• Study First Posted: 2010-10-06
• Primary Completion: 2013-04
• Study Completion: 2013-10
• Status Verified: 2017-03
• Last Update Submitted: 2017-03-28
• Last Update Posted: 2017-03-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• BMI ≥ 30 kg/M2
• Apne - hypopnea index (AHI) > 10
• No significant comorbidities
• Abel to exercise

Exclusion Criteria

• Inability to exercise due to musculoskeletal conditions
• Known ischemic cardiovascular disease
• Drug abuse
• Mental illnesses

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Aerobic Interval Training	Aerobic Interval training	Patients randomized to training will meet for supervised aerobic interval training three times per week for 3 months. The interval training session consists of 10 minutes warm up and continues with 4 x 4 minutes of high intensity intervals at 90-95% of maximal heart rate
Control	Control	Patients will receive standard medical treatment at the University Hospital lung department.

Primary Outcome Measures

Name	Time	Method
Apnea-hypopnea index change	Baseline, 3 and 6 months	Measured by Polysomnography

Secondary Outcome Measures

Name	Time	Method
Sleep quality	Baseline, 3 and 6 months	Epworth Sleepiness Scale

Trial Locations

Locations (1)

Norwegian University of Science and Technology; 🇳🇴 Trondheim, Norway