Comparison of cinnarizine and topiramate in migraine prophylaxis

Not Applicable

Conditions: Condition 1: Common migraine. Condition 2: Classical migraine.
Migraine without aura [common migraine]
Migraine with aura [classical migraine]

Registration Number: IRCT201201028323N5

Lead Sponsor: Vice-chancellor for research, Kermanshah University of Medical Sciences and Health Services

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 126

Inclusion Criteria

more than 4 and less than 10 attacks monthly ; interval between attacks more than 48 hours ; age at the onset of headache less than 50 years ; age 18-65 years ; not being pregnant or breast feeding ; discontinuation of other prophylactic drugs one month prior to the study
Exclusion criteria: non-migraine headaches ; overuse of medications in migraine attacks (consumption of NSAID, Ergots or Triptans more than 8 days a month) ; substance and alcohol abuse ; illiteracy of patients and their family (unable to fill diaries)

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of headache. Timepoint: in each migraine attack. Method of measurement: patient will record the headache severity in daily notes as VAS (from 1 to 10) & physician registers them every 4 weeks.;Duration of migraine attack. Timepoint: in each migraine attack. Method of measurement: patient records the hours of headache in each attack , physician register them every 4 weeks.;Headache frequency. Timepoint: every 4 week. Method of measurement: According to patients daily notes.;Analgesic use. Timepoint: every 4 week. Method of measurement: According to patients daily notes.

Secondary Outcome Measures