跳至主要内容
临床试验/CTRI/2023/05/052428
CTRI/2023/05/052428已完成不适用

COMPARISON OF MYOCARDIAL DEFORMATION IMAGING IN PATIENTS BETWEEN HYPERTROPHIC CARDIOMYOPATHY AND CHRONIC KIDNEY DISEASE ASSOCIATED WITH LEFT VENTRICULAR HYPERTROPHY

DEPARTMENT OF CARDIOLOGY1 个研究点 分布在 1 个国家目标入组 56 人开始时间: 2023年10月5日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
56
试验地点
1
主要终点
To evaluate and compare the Global longitudinal strain and systolic and diastolic strain rate patterns in patients with HCM and LVH secondary to CKD

研究概览

简要总结

Speckle Tracking Echocardiography is a useful technique in distinguishing pathologic and physiological hypertrophy by changes in strain rate pattern. There is no data comparing the myocardial deformation patterns in Hypertrophic Cardiomyopathy and secondary left ventricular hypertrophy in Chronic Kidney Disease. Therefore evaluation of  Global longitudinal strain and strain rates in early stage of disease can help in prognosis and  modification of the treatment.

PRIMARY OUTCOME: To evaluate and compare Global longitudinal strain and systolic and diastolic strain rate patterns in patients with HCM and LVH secondary to CKD

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Patients diagnosed with HCM and hypertrophy secondary to renal failure-CKD (stage III, IV and V) CKD patients with IVS diastolic thickness of 1.5cm.

排除标准

  • LVH secondary to any other reasons except for CKD Dilated cardiomyopathy Acute decompensated Heart Failure Poor echo window.

结局指标

主要结局

To evaluate and compare the Global longitudinal strain and systolic and diastolic strain rate patterns in patients with HCM and LVH secondary to CKD

时间窗: 1 YEAR

次要结局

未报告次要终点

研究者

发起方
DEPARTMENT OF CARDIOLOGY
申办方类型
Research institution and hospital

研究点 (1)

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