Comparison of Heart function using new echocardiographic indices between patients with genetically thickened cardiac muscle condition and severe kidney disease patients.

Completed

• Conditions: Other hypertrophic cardiomyopathy,

• Registration Number: CTRI/2023/05/052428
• Lead Sponsor: DEPARTMENT OF CARDIOLOGY

Brief Summary

Speckle Tracking Echocardiography is a useful technique in distinguishing pathologic and physiological hypertrophy by changes in strain rate pattern. There is no data comparing the myocardial deformation patterns in Hypertrophic Cardiomyopathy and secondary left ventricular hypertrophy in Chronic Kidney Disease. Therefore evaluation of  Global longitudinal strain and strain rates in early stage of disease can help in prognosis and  modification of the treatment.

PRIMARY OUTCOME: To evaluate and compare Global longitudinal strain and systolic and diastolic strain rate patterns in patients with HCM and LVH secondary to CKD

Detailed Description

Not available

Study Timeline

• Study Start: 2023-10-05
• Last Update Posted: 2024-01-07
• Study Completion: 2024-03-15

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

Patients diagnosed with HCM and hypertrophy secondary to renal failure-CKD (stage III, IV and V) CKD patients with IVS diastolic thickness of 1.5cm.

Exclusion Criteria

LVH secondary to any other reasons except for CKD Dilated cardiomyopathy Acute decompensated Heart Failure Poor echo window.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate and compare the Global longitudinal strain and systolic and diastolic strain rate patterns in patients with HCM and LVH secondary to CKD	1 YEAR

Trial Locations

Locations (1)

KASTURBA HOSPITAL; 🇮🇳 Udupi, KARNATAKA, India

KASTURBA HOSPITAL

🇮🇳Udupi, KARNATAKA, India

SREESHA P

Principal investigator

7560865197

sreesha.mchpmpl2022@learner.manipal.edu