The Effects of preoperative continue Angiotensin-Converting Enzyme Inhibitors/Angiotensin Receptor Blockers on postoperative Acute Kidney Injury after Coronary Artery Bypass Graft Surgery
- Registration Number
- TCTR20210824011
- Lead Sponsor
- /A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 250
Inclusion Criteria
1. Coronary artery bypass graft surgery with cardiopulmonary bypass.
2. Aged at least 18 years.
Exclusion Criteria
1. Involve aortic surgery.
2. Emergency surgery.
3. Prior sternotomy.
4. Prior expose contrast agent within 72 hr preoperative
5. Off-pump CABG converted to on-pump CABG
6. Preoperative serum creatinine more than or equal to 2 mg/dL., need preoperative dialysis or prior kidney transplant.
7. Preoperative ECMO or Need post-op ECMO in 7 days after surgery
8. Died within 7 days postoperative
9. Incomplete data collection
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The effect of continue ACEI/ARB and AKI as KDIGO staging after CABG surgery with CPB at ICU admission (T1), postoperative day 1, 2, and 5-7 (T2, T3, T4). Retrospective chart review between January 1, 2018, to May 31, 2021. Regression analysis
- Secondary Outcome Measures
Name Time Method 1.Postoperative vasoactive inotropic score (VIS) at ICU admission (T1), postoperative day 1, and day 2 (T2, T3). Retrospective chart review between January 1, 2018, to May 31, 2021 Regression analysis,2.Postoperative vasodilator within 24 h Retrospective chart review between January 1, 2018, to May 31, 2021 Regression analysis,3. In hospital morbidity Retrospective chart review between January 1, 2018, to May 31, 2021 Regression analysis,4.Hospital length of stay and condition of discharge Retrospective chart review between January 1, 2018, to May 31, 2021 Regression analysis,5. In hospital mortality Retrospective chart review between January 1, 2018, to May 31, 2021 Regression analysis,6. 30-day readmission and mortality Retrospective chart review between January 1, 2018, to May 31, 2021 Regression analysis