NL-OMON49528招募中不适用
Pharmacokinetic and pharmacodynamic target attainment of amoxicillin(-clavulanic acid) in pleural empyema fluid and complicated parapneumonic effusion - Empyema-study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Age >= 18 years
- •Diagnosed with pleural empyema or complicated parapneumonic effusion, based on
- •the criteria mentioned below, and in need of pleural fluid drainage.
- •o presence of pus or positive Gram*s stain or culture from the pleural fluid.
- •o pleural pH<7.2 or pleural fluid glucose value <2.2 mmol/l or pleural fluid
- •LDH value >1000 IU/L
- •Receiving IV amoxicillin 1000mg 4 times daily or amoxicillin-clavulanic acid
- •1000/200mg 4 times daily; dosage if necessary adapted to renal function
- •Able and willing to give informed consent (or consent by family member or legal
- •representative)
排除标准
- •Critically ill patients admitted to the ICU, or patients of the general ward
- •who became critically ill and got transferred to the ICU during the duration of
- •Pre-existing ipsilateral pleural effusion or other cause of pleural effusion
- •(e.g. cancer) more likely.
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