NL-OMON24554尚未招募不适用
Pharmacokinetic and pharmacodynamic target attainment of amoxicillin(-clavulanic acid) in pleural empyema fluid and complicated parapneumonic effusion
ot applicable.0 个研究点目标入组 20 人开始时间: 待定最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
入选标准
- •Age = 18 years
- •-Diagnosed with pleural empyema or complicated parapneumonic effusion, based on the criteria mentioned below, and in need of pleural fluid drainage.
- •opresence of pus or positive Gram’s stain or culture from the pleural fluid.
- •opleural pH<7.2 or pleural fluid glucose value <2.2 mmol/l or pleural fluid LDH value >1000 IU/L
- •-Receiving IV amoxicillin 1000mg 4 times daily or amoxicillin-clavulanic acid 1000/200mg 4 times daily; dosage if necessary adapted to renal function
- •-Able and willing to give informed consent (or consent by family member or legal representative)
排除标准
- •-Critically ill patients admitted to the ICU, or patients of the general ward who became critically ill and got transferred to the ICU during the duration of the study.
- •-Pre-existing ipsilateral pleural effusion or other cause of pleural effusion (e.g. cancer) more likely.
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