EUCTR2021-006860-26-NL
Active, not recruiting
Phase 1
Pharmacokinetic and pharmacodynamic target attainment of cefuroxime in adult patients on general wards with different degrees of renal function: a prospective observational cohort study - Target Attainment Cefuroxime
oordwest Ziekenhuisgroep0 sites45 target enrollmentJanuary 5, 2022
ConditionsBacterial infectionsTherapeutic area: Diseases [C] - Bacterial Infections and Mycoses [C01]
DrugsCefuroxime
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Bacterial infections
- Sponsor
- oordwest Ziekenhuisgroep
- Enrollment
- 45
- Status
- Active, not recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Receiving cefuroxime therapy intravenous (iv) as part of standard care
- •Age \= 18 years
- •Admitted to a general ward of Noordwest Ziekenhuisgroep – location Alkmaar
- •Informed consent is obtained
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range 45
- •F.1\.3 Elderly (\>\=65 years) yes
- •F.1\.3\.1 Number of subjects for this age range 45
Exclusion Criteria
- •Mentally incapacitated patients, i.e. a minor or legally incompetent adult
- •Renal replacement therapy during treatment with cefuroxime
- •Patients admitted to the intensive care unit (ICU)
- •Severely burned patients, defined as a burned surface \= 10%
- •Patients with cystic fibrosis
- •Informed consent is not obtained
Outcomes
Primary Outcomes
Not specified
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