Target attainment of the antibiotic cefuroxime for the treatment of hospital acquired infections.

Phase 1

• Conditions: Bacterial infections; Therapeutic area: Diseases [C] - Bacterial Infections and Mycoses [C01]

• Registration Number: EUCTR2021-006860-26-NL
• Lead Sponsor: oordwest Ziekenhuisgroep

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-01-05
• Last Update Posted: 10 January 2022

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• Receiving cefuroxime therapy intravenous (iv) as part of standard care
• Age = 18 years
• Admitted to a general ward of Noordwest Ziekenhuisgroep – location Alkmaar
• Informed consent is obtained
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 45
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 45

Exclusion Criteria

• Mentally incapacitated patients, i.e. a minor or legally incompetent adult
• Renal replacement therapy during treatment with cefuroxime
• Patients admitted to the intensive care unit (ICU)
• Severely burned patients, defined as a burned surface = 10%
• Patients with cystic fibrosis
• Informed consent is not obtained

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified