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Clinical Trials/NCT02458573
NCT02458573
Completed
Phase 4

Comparison of the Effects of Continuous Epidural Analgesia and Continuous Intravenous Analgesia on Postoperative Bowel Movement in Patients Undergoing Laparoscopic Gastrectomy

Yonsei University1 site in 1 country86 target enrollmentJune 4, 2015
ConditionsGastric Cancer

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Gastric Cancer
Sponsor
Yonsei University
Enrollment
86
Locations
1
Primary Endpoint
the time to first gas passing after surgery
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

The investigators hypothesized that sympatholytic effect of epidural analgesia would attenuate the hemodynamic instability and decrease in the splanchnic blood flow caused by pneumoperitoneum during laparoscopic surgery. This study is to compare the effect of epidural analgesia and intravenous analgesia on postoperative bowel movement in patients undergoing laparoscopic gastrectomy.

Registry
clinicaltrials.gov
Start Date
June 4, 2015
End Date
March 28, 2016
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • patient between 20 and 70 of age with ASA physical status Ⅰ-Ⅲ
  • gastric cancer patient undergoing laparoscopic gastrectomy

Exclusion Criteria

  • ASA physical status Ⅳ
  • bradycardia (\< 60 bpm), arrhythmia
  • uncompensated heart failure
  • hepatic failure (Child-Pugh score B)
  • renal failure (eGFR MDRD \< 60 ml/min/1.73m2)

Outcomes

Primary Outcomes

the time to first gas passing after surgery

Time Frame: within 5days after surgery

Outcome will be assessed by a investigator blinded to the study group.

the time to resume water intake after surgery

Time Frame: within 5days after surgery

Outcome will be assessed by a investigator blinded to the study group.

soft diet intake after surgery

Time Frame: within 5days after surgery

Outcome will be assessed by a investigator blinded to the study group.

Secondary Outcomes

  • postoperative pain(immediately after surgery to 48 hours)

Study Sites (1)

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