Comparison of the Effects of Continuous Epidural Analgesia and Continuous Intravenous Analgesia on Postoperative Bowel Movement in Patients Undergoing Laparoscopic Gastrectomy

Phase 4

Completed

• Conditions: Gastric Cancer
• Interventions: Other: continuous epidural analgesia; Other: continuous intravenous analgesia

• Registration Number: NCT02458573
• Lead Sponsor: Yonsei University

Brief Summary

The investigators hypothesized that sympatholytic effect of epidural analgesia would attenuate the hemodynamic instability and decrease in the splanchnic blood flow caused by pneumoperitoneum during laparoscopic surgery. This study is to compare the effect of epidural analgesia and intravenous analgesia on postoperative bowel movement in patients undergoing laparoscopic gastrectomy.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2015-05-26
• Study First Submitted QC: 2015-05-27
• Study First Posted: 2015-06-01
• Study Start: 2015-06-04
• Primary Completion: 2016-03-28
• Study Completion: 2016-03-28
• Status Verified: 2017-01
• Last Update Submitted: 2017-01-24
• Last Update Posted: 2017-01-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 86

Inclusion Criteria

• patient between 20 and 70 of age with ASA physical status Ⅰ-Ⅲ
• gastric cancer patient undergoing laparoscopic gastrectomy

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Exclusion Criteria

• ASA physical status Ⅳ
• bradycardia (< 60 bpm), arrhythmia
• uncompensated heart failure
• hepatic failure (Child-Pugh score B)
• renal failure (eGFR MDRD < 60 ml/min/1.73m2)

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
continuous epidural analgesia group	continuous epidural analgesia	-
continuous intravenous analgesia group	continuous intravenous analgesia	-

Primary Outcome Measures

Name	Time	Method
the time to first gas passing after surgery	within 5days after surgery	Outcome will be assessed by a investigator blinded to the study group.
the time to resume water intake after surgery	within 5days after surgery	Outcome will be assessed by a investigator blinded to the study group.
soft diet intake after surgery	within 5days after surgery	Outcome will be assessed by a investigator blinded to the study group.

Secondary Outcome Measures

Name	Time	Method
postoperative pain	immediately after surgery to 48 hours	numerical rating scale 0 (no pain) to 10 (worst pain)

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine; 🇰🇷 Seoul, Korea, Republic of