Short-term effect of positive airway pressure therapy in patients with atrial fibrillation and sleep-disordered breathing
- Conditions
- Atrial fibrillation, heart failure, sleep disordered breathing
- Registration Number
- JPRN-UMIN000032188
- Lead Sponsor
- Juntendo University Graduate School of Medicine Cardiovascular Respiratory Sleep Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Not provided
1) LV systolic dysfunction (LV ejection fraction is less than or equal to 45% on echocardiogram) 2) Severe organic valvular diseases 3) Patients who have acute myocardial infarction, ICD or CRT device implantation, cardiac surgery including PCI and transcatheter aortic valve intervention during the 3 months preceding randomization. 4) Patients who have a possibility for pacemaker, ICD or CRT device implantation or cardiac or non-cardiac surgery including percutaneous coronary intervention, transcatheter aortic valve intervention in 3 months 5) Life-threatening diseases (uncured malignancy, severe chronic pulmonary diseases with oxygen inhalation or specific medication, and end stage renal disease with dialysis) 6) Patients who have already been initiated into PAP therapy 7) Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in E/e' by echocardiogram during 6 months and change in the H/M ratio and the wash out rate of 123I-MIBG during 6 months
- Secondary Outcome Measures
Name Time Method