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Short-term effect of positive airway pressure therapy in patients with atrial fibrillation and sleep-disordered breathing

Not Applicable
Conditions
Atrial fibrillation, heart failure, sleep disordered breathing
Registration Number
JPRN-UMIN000032188
Lead Sponsor
Juntendo University Graduate School of Medicine Cardiovascular Respiratory Sleep Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
60
Inclusion Criteria

Not provided

Exclusion Criteria

1) LV systolic dysfunction (LV ejection fraction is less than or equal to 45% on echocardiogram) 2) Severe organic valvular diseases 3) Patients who have acute myocardial infarction, ICD or CRT device implantation, cardiac surgery including PCI and transcatheter aortic valve intervention during the 3 months preceding randomization. 4) Patients who have a possibility for pacemaker, ICD or CRT device implantation or cardiac or non-cardiac surgery including percutaneous coronary intervention, transcatheter aortic valve intervention in 3 months 5) Life-threatening diseases (uncured malignancy, severe chronic pulmonary diseases with oxygen inhalation or specific medication, and end stage renal disease with dialysis) 6) Patients who have already been initiated into PAP therapy 7) Pregnancy

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in E/e' by echocardiogram during 6 months and change in the H/M ratio and the wash out rate of 123I-MIBG during 6 months
Secondary Outcome Measures
NameTimeMethod
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