Efects of Noninvasive Mechanical Ventilation and Conventional Mechanical Ventilation in Patients With Severe Comunity Pneumonia
Not Applicable
Terminated
- Conditions
- Community Acquired Pneumonia.Acute Hypoxemic Respiratory Failure
- Registration Number
- NCT00523497
- Lead Sponsor
- Hospital Privado del Sur
- Brief Summary
The purpose of this study is to determine whether the noninvasive ventilation is more effective in the treatment of severe comunity acquired pneumonia in comparison with the conventional mechanical ventilation with orotracheal intubation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
The criteria for the diagnosis of SCAP included:
- Blood systolic pressure lower than 90 mmHg or blood diastolic pressure lower than 60 mmHg
- RR higher than 30 breaths per minute
- PaO2/FiO2 lower than 250 while breathing through a Venturi mask with a 50% inspired oxygen fraction (FiO2)
- Bilateral or multiple lobar infiltrations evidenced by thorax X-ray, and
- Use of vasopressor drugs
Exclusion Criteria
Exclusion criteria included:
- COPD
- Asthma
- Acute cardiogenic pulmonary edema
- Severe haemodynamic instability (arterial systolic pressure lower than 70 mmHg) or requirements of vasoactive drugs
- Glasgow score equal to or lower than 9 or requiring OTI for airway protection or for recent pulmonary resucitation
- Antecedents of respiratory failure resulting from neuromuscular pathology
- Failure of two or more organs
- Facial deformities; and
- Recent facial, aesophagic and gastric surgeries
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method The primary aim of this study was to compare the effects of NIMV on mortality rate and length of stay at the ICU with the effects of CMV 3 years
- Secondary Outcome Measures
Name Time Method The secondary aims were to evaluate the incidence and the complications of OTI as well as to compare the improvements in the gas exchange. 3 years
Trial Locations
- Locations (1)
Hospital Privado del Sur
🇦🇷Bahía Blanca, Buenos Aires, Argentina