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Clinical Trials/NCT03567967
NCT03567967
Completed
Not Applicable

The EValuating Interventions in Diabetogenic Environments Through Natural Controlled Experiments (EVIDENCE) Trial

Stanford University2 sites in 1 country313 target enrollmentMay 31, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cardiovascular Diseases
Sponsor
Stanford University
Enrollment
313
Locations
2
Primary Endpoint
Change in fruit and vegetable consumption
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

We aim to examine whether a purchasing incentive for healthy foods has the same effect on dietary intake in a community with and a community without a purchasing penalty for unhealthy foods. We will perform a randomized non-inferiority trial in two locations, San Francisco (SF) and Los Angeles (LA) to test whether a voucher for purchasing fresh fruits and vegetables has a similar effect in LA and in SF, where the former does not but the latter does have a tax on sugar-sweetened beverages. Participants will be recruited from 4 neighborhoods (N=312) with 2 SF neighborhoods (exposed to the SSB tax) and 2 LA neighborhoods (not exposed to the SSB tax).

Detailed Description

We will test the hypothesis that a positive incentive for healthy foods (fresh fruits and vegetables, F\&Vs) will be utilized as effectively in a community without a purchasing penalty for unhealthy foods (a sugar-sweetened beverage \[SSB\] tax) as in a community with a purchasing penalty for unhealthy foods (a SSB tax). Our experiment will test the empirically-driven hypothesis in a real-world setting through a noninferiority design: comparing the impact of F\&V vouchers in two counties, one without (Los Angeles) and one with (San Francisco) a SSB tax. Each study participant will receive four paper vouchers per month for a total of six months. Each of these vouchers can be redeemed for fresh or frozen fruits and vegetables at a number of specified local corner stores, supermarkets, or farmer's markets. Half of these participants will receive and spend these vouchers in an environment which has implemented a SSB tax (SF); the other half will receive and spend these same vouchers in a non-tax environment (LA). Each individual participant will be enrolled in the study for a total of seven months from initial orientation and participant consent (M0) to final data collection during final month of intervention (M6). We are using a non-inferiority trial design. We are aiming to test whether there is a significant difference in total cup-equivalents of F\&V intake in LA participants as compared to SF participants when given F\&V vouchers. That is, we aim to test whether the F\&V voucher is less effective in LA than in SF. This is important to test because it has been purported that SF has a unique food environment with high accessibility to fresh F\&V through farmer's markets and a plethora of corner stores, as well as a SSB tax that discourages less healthy foods, potentially leaving more funds for healthier F\&Vs. Thus, we aim to determine the change in consumption of F\&V in LA participants is non-inferiority to that of SF participants, when both are given F\&V vouchers.

Registry
clinicaltrials.gov
Start Date
May 31, 2018
End Date
September 9, 2019
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Christopher Gardner

Assistant Professor of Medicine

Stanford University

Eligibility Criteria

Inclusion Criteria

  • Understand English sufficiently to provide informed consent;
  • Provision of signed and dated informed consent form;
  • Stated willingness to comply with all study procedures and availability for the duration of the study;
  • Any gender, aged 21 years or older;
  • Have self-reported income ≤250% of the federal poverty level;
  • Have regular access to a mobile phone;
  • Have a safe and secure mailing address at which to receive vouchers;
  • Be a resident of the Counties of San Francisco or Los Angeles as defined by official municipal boundaries.

Exclusion Criteria

  • Currently participating in any other dietary or nutrition study that would impact his or her normal eating patterns;
  • Currently be enrolled in and receiving EatSF, CHIVES, or Vouchers4Veggies vouchers;
  • Has active diagnosis of cancer or congestive heart failure;
  • Is planning to move out of San Francisco or Los Angeles in the next 12 months;
  • Currently pregnant.
  • Currently live with and share a food budget with a current Vouchers4Veggies, EVIDENCE, or CHIVES study participant.

Outcomes

Primary Outcomes

Change in fruit and vegetable consumption

Time Frame: Month 0 to Month 6

Change in fruit and vegetable consumption from baseline (BL), i.e., before voucher receipt, to the end of the intervention at the end of month 6 (M6), i.e., during the final month of voucher receipt, measured by two 24-hour recalls at each data collection point (BL and M6).

Secondary Outcomes

  • Change in SSB consumption(Month 0 to Month 6)
  • Change in nutrition quality per HEI score(Month 0 to Month 6)
  • Overall percentage of vouchers redeemed(Month 0 to Month 6)
  • Change in nutrition quality per AHEI score(Month 0 to Month 6)
  • Change in overall caloric intake(Month 0 to Month 6)

Study Sites (2)

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