Brain Markers of Suicide Risk and Psychological Pain in Elderly Depressed Patients

Centre Hospitalier Universitaire de Nīmes1 site in 1 country60 target enrollmentAugust 18, 2017

ConditionsDepressive Disorder Suicide, Attempted

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Depressive Disorder
Sponsor: Centre Hospitalier Universitaire de Nīmes
Enrollment: 60
Locations: 1
Primary Endpoint: Brain functional activity during unfairness
Status: Completed
Last Updated: 6 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The main objective of this study is to show MRI functional and structural differences between depressed elderly patients with a history of attempted suicide compared to depressed elderly patients with no history of attempted suicide and to elderly subjects with no personal history of depression or attempted suicide (healthy controls).

Registry

clinicaltrials.gov

Start Date

August 18, 2017

End Date

December 13, 2019

Last Updated

6 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Centre Hospitalier Universitaire de Nīmes

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•The patient must have given their free and informed consent and signed the consent form
•be a member or beneficiary of a health insurance plan
•aged 60 years-old or more
•must be right-handed
•with a diagnosis of a current major depressive episode of moderate to severe severity according to diagnostic criteria.
•with or without a personal history of attempted suicide during life
•hospitalized or followed by a consultant in the department of Psychiatry of Nîmes University Hospital or in the Sophoras private clinic

Exclusion Criteria

•The subject is participating in an interventional study, or is in a period of exclusion determined by a previous study
•under safeguard of justice
•refuses to sign the consent
•It is impossible to give the subject informed information
•Current psychotic symptoms.
•Bipolar disorder.
•The subject presents an acute somatic decompensation incompatible with the realization of this study.
•The patient presents a mental confusion or a known Mini Mental State Examination score \<
•Central neurological disease known in particular degenerative pathology, severe cranial trauma and severe cerebrovascular disease.
•Schizophrenia and other known psychotic disorders.