Optimization of protein composition of pea protein hydrolysates regarding the bitterness and regulation of satiety
Not Applicable
Recruiting
- Conditions
- Overweight/Obesity
- Registration Number
- DRKS00033081
- Lead Sponsor
- eibniz-Institut für Lebensmittel-Systembiologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 20
Inclusion Criteria
20-45 years
-Written declaration of consent
-Men
-Non-smoker
-No chronic drug treatment
-BMI 25-30 kg/m2
Exclusion Criteria
- Female subjects, due to the effect of cycle-related fluctuations on satiety
hormones
- Smoker
- Current participation in another intervention study
- Diseases affecting nutrient absorption, digestive function, metabolism or
excretion
- Acute infectious diseases
- Chronic illnesses according to medical history (e.g. hepatitis B and C,
diabetes mellitus)
- Gastrointestinal complaints
- History of diverticulosis, constipation
- Intolerance or allergy to any component of the intervention
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Determination of the subjects' subjective feeling of hunger before and after administration of the hydrolysates in each intervention arm by using visual analogue scales.<br>
- Secondary Outcome Measures
Name Time Method - Determination of the subjects' energy intake with a subsequent ad libitum<br> breakfast by using optiDiet in each intervention arm<br>- Examination of gastric emptying with the aid of a 13C-Na-acetate breath <br> test in each intervention arm<br>- Determination of blood plasma concentrations of the hormones ghrelin, <br> serotonin, GLP 1, CCK, insulin, and plasma glucose in each intervention <br> arm<br>- Sensory test to determine the individual bitter threshold value by using questionnaires