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临床试验/CTRI/2023/03/050744
CTRI/2023/03/050744尚未招募不适用

Comparison of Perioperative Analgesic Efficacy and Quality of recovery on addition of lignocaine with adrenaline to Levobupivacaine in Ultrasound Guided Supraclavicular Block for Upper Limb Orthopaedic Surgeries: A Randomised Control Study

Government medical college1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2023年1月4日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
80
试验地点
1
主要终点
2 to measure total analgesic requirement

研究概览

简要总结

Current study is to research the effect of lignocaine as an adjuvant to levobupivacaine for advancement of scientific knowledge.

The aim of this study is to compare the perioperative efficacy and recovery quality of ultrasound guided supraclavicular block  administered using levobupivacaine with or without lignocaine with adrenaline for conduct of upper limb surgeries. Patients will be randomly divided into two groups (LLB and LL) with 40 patients in each group. The nerve bundle will be identified and infiltrated with the local anesthetic after negative aspiration for blood and no intraneural spread as visualized with ultrasound. Group LB will receive  28 mL of 0.5% levobupivacaine and 2 mL of normal saline  while the Group LLB will receive 14 ml of 0.5% levobupivacaine,14 ml of lignocaine with adrenaline  and 2 ml of normal saline making a total 30 ml of anestheticsolution. Patients will be observed for onset and duration of spinal and motor blockade in both the groups. The hemodynamic changes and side effects if any, would also be noted and compared amongst two groups. Postoperative analgesia requirement with rescue analgesia using injection Paracetamol 1gm intravenously.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • ASA I , II, III.

排除标准

  • Infection at local sites, hypersensitivity to Local Anaesthetic drugs, per existing neuropathy, bleeding disorders,pregnancy, any hepatic , renal,neurological,psychiatric or neuromuscular diseases.

结局指标

主要结局

2 to measure total analgesic requirement

时间窗: 1) time at which first rescue analgesia given will be recorded. | 2) total analgesia required in 24 hours.

1 To measure first rescue analgesia

时间窗: 1) time at which first rescue analgesia given will be recorded. | 2) total analgesia required in 24 hours.

次要结局

  • 1)to compare QoR score in both groups.(2) to blockade characteristics)

研究者

申办方类型
Government medical college

研究点 (1)

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