Comparison of paracetamol and ketamine for post-operative pain management in patients undergoing total abdominal hysterectomy

Not Applicable

• Conditions: Post operative analgesia after total abdominal hysterectomy.; Acquired absence of uterus; Z90.710

• Registration Number: IRCT2012103011319N1
• Lead Sponsor: Research Deputy, Tehran University of Medical Sciences (TUMS)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

inclusion criteria: 1-Volunteers ages between 25-65; 2- American Society of Anesthesiologist class (ASA) I, II Physical Status; 3- Scheduled for total abdominal hysterectomy surgery; 4- Written informed consent , based on Tehran University Mdical Sciences , Ethical Committee Appproved Study design.

Exclusion Criteria

1-Out of 25-65 ages limitations; 2- Addiction to opiates; 3- Known allergy to acetaminophen or ketamine; 4- History of alcoholism and drug abuse; 5- History of hepatic disease; 6- Dispensing of patient any time after informed consent or lack of patient consent; 7- History of sizure

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain. Timepoint: At recovery room, 4, 6, 12 and 24 o'clock after surgery. Method of measurement: Visual Analoge Scsale.

Secondary Outcome Measures

Name	Time	Method
The patients will evaluate for Sedation, Nausea and Vomiting, additional requirement for analgesia and probable complication during study includes of: pruritus and other complication in both groups. Timepoint: At recovery room, 4, 6, 12 and 24 o'clock after surgery. Method of measurement: Score of seadtion and nausea and vomiting type and dosage of additional analgesic.