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Driving pressure guided positive end expiratory pressure (PEEP) vs fixed PEEP in preventing lung collapse

Not Applicable
Completed
Conditions
Health Condition 1: O- Medical and SurgicalHealth Condition 2: N998- Other intraoperative and postprocedural complications and disorders of genitourinary system
Registration Number
CTRI/2022/10/046764
Lead Sponsor
AIIMS
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
82
Inclusion Criteria

1) Patients undergoing laparoscopic urological and gynaecological surgeries.

2) ASA PS 1 & 2 patients

Exclusion Criteria

1) Patients refusal to participate in the study

2) Previous thoracic surgeries or massive blood loss >40ml/Kg

3) Patients with ARDS / lung injury / COPD / chronic lung disease.

4) Recent history of upper respiratory tract infection/ history of bronchial asthma

5) Significant cardiac, renal or hepatic disease.

BMI <18 or >30 Kg/m2

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To identify whether an individualized PEEP guided by driving pressures can reduce the magnitude of postoperative ( 30 minutes after extubation) lung atelectasis as compared to a fixed PEEP assessed by change in modified lung ultrasound scoreTimepoint: 24 hours after extubation of the patient
Secondary Outcome Measures
NameTimeMethod
Post operative oxygen requirementTimepoint: Post operative period
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