The effect of oral melatonin supplementation on the number and quality of oocytes and embryos in infertile women with endometriosis
Phase 3
Recruiting
- Conditions
- Endometriosis.Endometriosis
- Registration Number
- IRCT20171209037794N5
- Lead Sponsor
- Babol University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
Infertile women 20 to 40 years old
under ART treatment along with laparoscopy or ultrasound report indicating the presence of endometriosis
Exclusion Criteria
Premature ovarian failure.
severe male factor according to the criteria (WHO), sperm count less than 15 million per milliliter and motility less than 50% and normal morphology less than 4%.
Occurrence of complications and drug sensitivity such as (fatigue, headache, blurred vision, nausea, diarrhea).
Diagnosis of adenomyosis and chronic diseases including thyroid, adrenal diabetes, current malignancy or history of malignancy, uterine myoma and PID .
Patients whose infertility is due to obstruction problems, genetic problems or hormonal problems.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber and quality of embryos. Timepoint: 24 hours after ICSI. Method of measurement: Microscopic assay.
- Secondary Outcome Measures
Name Time Method The number and quality of oocytes. Timepoint: oocyte pick up day. Method of measurement: Microscopic Assay.;Fertilization rate. Timepoint: 24 hours after ICSI. Method of measurement: Microscopic Assay.