Evaluating the efficacy of dissolving xylitol chewable tablets versus xylitol chewing gum on bacterial count, plaque accumulation and gingival inflammation in senior citizens.

Phase 2

Not yet recruiting

• Conditions: Chronic gingivitis,

• Registration Number: CTRI/2025/06/089570
• Lead Sponsor: Dr Tannu Kumari

Brief Summary

This randomized, double-blind, parallel-group clinical trial aims to evaluate and compare the efficacy of dissolving xylitol chewable tablets and chewing gum on salivary bacterial count, plaque accumulation, and gingival inflammation in senior citizens. 96 participants aged 60 years and above will be enrolled and randomly assigned to one of two intervention groups. Clinical parameters will be recorded at baseline and after 30 days of intervention.

This study aims to evaluate the efficacy of dissolving xylitol chewable tablets compared to xylitol chewing gum as a substitute for toothbrushing and mouth rinsing in countering bacterial levels, plaque formation, and gingival inflammation in elderly people.

The null hypothesis is that the xylitol-dissolving chewable tablets and xylitol chewing gum are equally effective on salivary Streptococcus mutans bacterial count, plaque formation, and gingival inflammation among senior citizens.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-06-24
• Study Start: 2025-07-07

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 96

Inclusion Criteria

Inclusion criteria involved at least 20 natural teeth and mild to moderate gingival inflammation.

Exclusion Criteria

Subjects with systemic illness impacting oral health, history of known allergy to xylitol, or intake of antibiotics or antimicrobial mouthwashes over the last three months were excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bacterial count,Plaque accumulation, Gingival inflammation	0-30 days

Secondary Outcome Measures

Name	Time	Method
salivary pH or flow rate	0-30 days

Trial Locations

Locations (1)

Vedic Vanaprastha Ashram; 🇮🇳 Moradabad, UTTAR PRADESH, India

Vedic Vanaprastha Ashram

🇮🇳Moradabad, UTTAR PRADESH, India

TANNU KUMARI

Principal investigator

8126783502

tankashra@gmail.com