Morfologie en functie van de hypothalamus na glucose inname door proefpersonen voor en na het gebruik van een hoogcalorisch dieet gedurende vijf dagen.
Recruiting
- Conditions
- diabetes type 2 suikerziekteouderdomssuikerziektediabetes
- Registration Number
- NL-OMON21031
- Lead Sponsor
- Prof. dr. H. Pijl, internist-endocrinoloog
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
1. Healthy males;
2. Healthy diet;
Exclusion Criteria
1. Use of medication known to affect glucose metabolism (for example prednisone) or lipid metabolism;
2. History of genetic or psychiatric disease (e.g. fragile X syndrome, major depression) that affects the brain;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. FMRI scans of hypothalamus;<br /><br>2. Polysomnography/MSLT.<br>
- Secondary Outcome Measures
Name Time Method 1. Metabolomics;<br /><br>2. Inflammatory markers;<br /><br>3. Oral glucose tolerance test;<br /><br>4. Gut hormones.