NCT03171805Unknown不适用
Post-balloon Occluded Retrograde Transvenous Obliteration Use of Propranolol for the Prevention of Worsening of Esophageal Varices in Patients With Isolated Gastric Varices
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 74
- 试验地点
- 1
- 主要终点
- Worsening of esophageal varices rate
研究概览
简要总结
Balloon-occluded retrograde transvenous obliteration (BRTO) has been effective method to manage gastric varices. However, more than one third of patients after BRTO treatment experienced worsening of esophageal varices. The present study was designed to evaluate the effect of post-BRTO propranolol adminstration on the change of esophageal varices.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of liver cirrhosis
- •Clinical diagnosis of isolated gastric varices
- •The presenec of spontaneous portosystemic shunt
排除标准
- •Contradictions to Propranolol
- •Balloon occluded retrograde transvenous obliteration was failed
研究组 & 干预措施
Propranolol group
Experimental
Propranolol was given after patients with cirrhosis and isolated gastric varices underwent balloon occluded retrograde transvenous obliteration successfully.
干预措施: Propranolol (Drug)
结局指标
主要结局
Worsening of esophageal varices rate
时间窗: 3 years
Analysis
次要结局
- Mortality rate(3 years)
- Worsening of ascites rate(3 years)
- Variceal rebleeding rate(3 years)
研究者
luo xuefeng
Attending doctor
West China Hospital
研究点 (1)
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