Post-exercise Appetite Responses in Type 1 Diabetes

Not Applicable

Completed

• Conditions: Type 1 Diabetes Mellitus
• Interventions: Dietary Supplement: Meal composition - Low versus high GI.

• Registration Number: NCT02208115
• Lead Sponsor: Northumbria University

Brief Summary

The investigators hypothesise that manipulating the glycaemic index of the meal after exercise will influence the acute appetite responses of Type 1 diabetes individuals

Detailed Description

Not available

Study Timeline

• Study Start: 2013-11
• Primary Completion: 2013-11
• Study Completion: 2013-11
• Study First Submitted: 2014-07-25
• Status Verified: 2014-08
• Study First Submitted QC: 2014-08-01
• Last Update Submitted: 2014-08-01
• Study First Posted: 2014-08-04
• Last Update Posted: 2014-08-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 10

Inclusion Criteria

• Aged between 18-50 years old (male or female).
• Free from any diabetes related complications (apart from mild background diabetic retinopathy).
• HbA1c <8.5%.
• Not taking any prescribed medication other than insulin, and treated with a stable insulin regimen composed of a combination of slow/long acting insulin (glargine or detemir) and fast-acting insulin analogues (lispro or aspart), for a minimum of 6 months before the start of the study.
• Demonstrate normal cardiac function in response to exercise.

Exclusion Criteria

• Aged younger than 18, or older than 50 years.
• Suffering from, or diagnosed with a diabetes related complication (apart from mild background diabetic retinopathy).
• HbA1c >8.5%.
• Currently taking prescribed medication, and not currently treated with a stable basal bolus regimen composed of a combination glargine or detemir, and lispro or aspart for at least 6 months before the start of the study.
• Failure to demonstrate normal cardiopulmonary responses during exercise, or have a medical condition which could prevent completion of exercise or be exacerbated because of.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Meal composition - Low GI	Meal composition - Low versus high GI.	Changing the glycaemic index of the meal consumed after exercise (High GI versus Low GI).
Meal composition - High GI	Meal composition - Low versus high GI.	Changing the glycaemic index of the meal consumed after exercise (High GI versus Low GI).

Primary Outcome Measures

Name	Time	Method
Acute subjective appetite responses	4 hours post-exercise	Subjective appetite ratings via Visual Analogue Scales

Trial Locations

Locations (1)

Clinical Research Facility, Royal Victoria Infirmary; 🇬🇧 Newcastle upon Tyne, Tyne and Wear, United Kingdom