Exercise for Preventing the Metabolic Syndrome in Latinoamerican Amerindians

Not Applicable

Completed

• Conditions: Obesity; Cardiovascular Risk Factor; Physical Activity
• Interventions: Behavioral: Concurrent training (CT)

• Registration Number: NCT03653468
• Lead Sponsor: Universidad Santo Tomas

Brief Summary

Despite exercise training decrease blood fasting glicaemy in 'average' terms, there is a wide inter-individual variability after exercise training explored mainly in adults but not in adults with prediabetes comorbidities. Thus, is yet unknown the effects and influence of the concurrent training (CT) eliciting responders (R) and non-responders (NR) cases (i.e., percentage of subjects who experienced a non-change/worsened response after training in some metabolic outcomes).

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-01
• Primary Completion: 2018-05-28
• Status Verified: 2018-08
• Study Completion: 2018-08-25
• Study First Submitted: 2018-08-28
• Study First Submitted QC: 2018-08-29
• Last Update Submitted: 2018-08-29
• Study First Posted: 2018-08-31
• Last Update Posted: 2018-08-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 28

Inclusion Criteria

• Written informed consent
• Interested in improving health and fitness

Exclusion Criteria

• Cardiovascular contraindications to exercise
• History of stroke, asthma or chronic obstructive pulmonary disease, muscle-skeletal disorders
• Smoking
• A compliance rate to the exercise program ≥ 70% was required for the participants in the intervention group to be included in the statistical analyses.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Endurance training plus resistant training	Concurrent training (CT)	Concurrent training

Primary Outcome Measures

Name	Time	Method
Fasting glucose	Baseline and 20-weeks immediately after the interventions ends	Change from Baseline in fasting glucose
Blood pressure	Baseline and 20-weeks immediately after the interventions ends	Change from baseline in Blood pressure
Total cholesterol	Baseline and 20-weeks immediately after the interventions ends	Change from baseline in Total cholesterol

Secondary Outcome Measures

Name	Time	Method
Six minutes walking test	Baseline and 20-weeks immediately after the interventions ends	Change from Baseline in six minutes walking test
Waist circumference	Baseline and 20-weeks immediately after the interventions ends	Change from Baseline in waist circumference
Lean mass	Baseline and 20-weeks immediately after the interventions ends	Change from Baseline in lean mass
Fat mass	Baseline and 20-weeks immediately after the interventions ends	Change from Baseline in fat mass
Heart rate at rest	Baseline and 20-weeks immediately after the interventions ends	Change from Baseline in heart rate at rest
Body mass	Baseline and 20-weeks immediately after the interventions ends	Change from Baseline in body mass

Trial Locations

Locations (1)

Cristian Alvarez; 🇨🇱 Los Lagos, Osorno, Chile