Barley and CKD in childre

Phase 2

• Conditions: Paediatrics; Kidney Disease

• Registration Number: PACTR202202482995099
• Lead Sponsor: the investigators

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-11-01
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1.Age between 6 and 14 years
2.Chronic kidney disease (CKD) stage 3-4 of any etiology, with an estimated GFR of <60mL/min/1.73m2 by Schwartz formula
3.Urine output more than 1ml/kg/h to avoid any possibility of fluid overload by administering barley extract.

Exclusion Criteria

1-Unwilling to participate in the study.
2-Comorbid diseases unrelated to CKD include diabetes mellitus, structural heart disease, active liver disease, pancreatic insufficiency, or Celiac disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Progression of CKD through assessment of change in measured creatinine clearance over six months

Secondary Outcome Measures

Name	Time	Method
Compliance, tolerability, and any clinical events<br>- Blood pressure control<br>- Growth and anthropometric parameters<br>- Proteinuria, lipid profile, glucose, urea, creatinine, Ca, P, and ALP <br>