Impact of Neuropsychological Alteration of Decision-making Abilities on the Functioning of Patients With Eating Disorders
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Eating Disorder
- Sponsor
- University Hospital, Montpellier
- Enrollment
- 340
- Locations
- 1
- Primary Endpoint
- Level of functional impairment assessed by the Work and Social Adjustment Scale (WSAS)
- Last Updated
- 4 years ago
Overview
Brief Summary
Eating disorders are multifactorial disorders currently conceptualized in a biopsychosocial model, but pathophysiology remains relatively unknown, and robust etiological models to guide treatment are therefore lacking. Different endophenotypes and neurocognitive vulnerability factors have been found in eating disorders including decision making abnormalities. The investigators hypothesize that decision making abnormalities are associated with a lower level of functioning and quality of life which could lead to social and interpersonal difficulties. The investigators also hypothesize that these anomalies are associated with a particular clinical profile (more restrictive profile, more hyperactivity, less insight on the disease and desire for care ...).
Detailed Description
The investigators will recruit a total of 340 patients with an eating disorder in the university hospital of Montpellier. * Participation consists of a one-day visit with a multidisciplinary assessment. No action is specific to research. This is the usual management of patients with eating disorders addressed to our department. * An ancillary study will be proposed, if the patient is addressed by his general practitioner for an annual evaluation. This second visit will be exactly the same as the initial visit.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patient with an eating disorder according to Diagnostic and Statistical Manuel of Mental disorders-V (DSM-V) criteria
- •Patient aged from 15 to 65 years
- •Patient who performs the day-hospital evaluation
- •Patient affiliated to a French social security system
- •Patient able to understand the nature, the aim and the methodology of the study
- •For minor one of the legal guardians gave his consent
Exclusion Criteria
- •Patient in an unstable somatic state (eg severe metabolic disorder making impossible or unreliable neuropsychological assessments)
- •Patient's refusal to participate
- •Patient on protective measures (guardianship or trusteeship)
- •Pregnant or nursing women. A dosage of beta human chorionic gonadotropin (βHCG) will be performed to ensure the absence of pregnancy.
Outcomes
Primary Outcomes
Level of functional impairment assessed by the Work and Social Adjustment Scale (WSAS)
Time Frame: Baseline
We aim to investigate the link between decision-making and daily functioning of patients with eating disorder.
Secondary Outcomes
- Quality of life assessed by the Eating disorder quality of life (EDQOL) scale.(Baseline)
- Level of functional impairment assessed by the clinician with the FAST scale(Baseline)
- Score to decision making test (Iowa gambling task)(At 12 months if patient is included in the ancillary study)
- Level of functional impairment assessed by the clinician with the Functional Assessment Staging Test (FAST) scale(Baseline)