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Clinical Trials/NCT04091477
NCT04091477
Completed
Not Applicable

Impact of Neuropsychological Alteration of Decision-making Abilities on the Functioning of Patients With Eating Disorders

University Hospital, Montpellier1 site in 1 country200 target enrollmentOctober 1, 2019
ConditionsEating Disorder

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Eating Disorder
Sponsor
University Hospital, Montpellier
Enrollment
200
Locations
1
Primary Endpoint
Level of functional impairment assessed by the clinician with the FAST scale
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Eating disorders are multifactorial disorders currently conceptualized in a biopsychosocial model, but pathophysiology remains relatively unknown, and robust etiological models to guide treatment are therefore lacking. Different endophenotypes and neurocognitive vulnerability factors have been found in eating disorders including decision making abnormalities. The investigators hypothesize that decision making abnormalities are associated with a lower level of functioning and quality of life which could lead to social and interpersonal difficulties. The investigators also hypothesize that these anomalies are associated with a particular clinical profile (more restrictive profile, more hyperactivity, less insight on the disease and desire for care ...).

Detailed Description

The investigators will recruit a total of 200 patients with an eating disorder in the university hospital of Montpellier. Participation consists of a one-day visit with a multidisciplinary assessment. No action is specific to research. This is the usual management of patients with eating disorders addressed to our department.

Registry
clinicaltrials.gov
Start Date
October 1, 2019
End Date
December 30, 2019
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Level of functional impairment assessed by the clinician with the FAST scale

Time Frame: 1 day

We aim to investigate the link between global functioning and decision making abnormalities of patients with eating disorder. The Functioning Assessment Short Test (FAST) is composed of 24 items assessing various dimensions of daily functionning. Each item is ranged from 0 (no difficulty) to 3 (major difficulty) like a likert scale. The FAST is subdivided in 6 subscales : Autonomy (from 0 to 12), Professional activity (from 0 to 15), Cognitive functioning (from 0 to 15), Finances (from 0 to 6), interpersonal relationships (from 0 to 18) and Hobbies (from 0 to 6). The total score is the sum of the 6 subscales from 0 to 72. A hight score reveal hight difficulties in daily functionning

Secondary Outcomes

  • Decision making assessed by the Iowa Gambling Task(1 day)
  • Level of central coherence assessed by the Rey Figure Test(1 day)
  • Level of cognitive flexibility assessed by the Brixton test(1 day)

Study Sites (1)

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