Evaluation of the Clinical, Neuropsychological and Psychosocial Situation of Patient With Eating Disorders.

Not Applicable

• Conditions: Eating Disorders
• Interventions: Other: Clinical assessment

• Registration Number: NCT02829645
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

Eating disorders (ED) are serious mental illnesses with an excess mortality and many affects in the quality of life of patients and thier relatives. Management of ED is very difficult : the prognosis remains relatively poor both in terms of remission rate and quality of life. In this context, the contribution of new strategies for pathophysiological exploration and the development of therapeutic options are crucial.

In this project the investigators aim to constitute un cohort of patients from a day unit specialized in the management of ED. A prospective follow-up will be offered to patients to assess their clinical and psycho-social evolution. The overall objective is to identify which factors are prognostic of clinical improvement of the ED. We also want to better characterize patients that will migrate from diagnosis to another.

Detailed Description

The investigators propose to assess, with a cohort of patients with ED the prognostic value of cognitive abnormalities associated with ED (cognitive flexibility and central coherence) They will recruit 370 patients suffering from a current ED (anorexia, bulimia, binge eating disorder, Eating disorder not otherwise specified).

Each patient will be reassessed every year for 3 years.

Study Timeline

• Study Start: 2012-02
• Primary Completion: 2014-10
• Status Verified: 2016-07
• Study First Submitted: 2016-07-07
• Study First Submitted QC: 2016-07-07
• Last Update Submitted: 2016-07-07
• Study First Posted: 2016-07-12
• Last Update Posted: 2016-07-12
• Study Completion: 2017-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 370

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Eating disorders	Clinical assessment	-

Primary Outcome Measures

Name	Time	Method
Frequency of remission rates	At the inclusion and at 12, 24 and 36 months	study of remission rates frequency at 12 months depending on the Brixton score assessed at baseline (assessment of cognitive flexibility). Remission is defined as disappearance of ED Diagnostic and Statistical Manual (DSM) criteria.

Secondary Outcome Measures

Name	Time	Method
score to another neuropsychological test (Iowa gambling task (IGT)	At the inclusion and at 12, 24 and 36 months	Study of remission rates frequency at 12 months depending on the IGT score (decision making) assessed at baseline
scores to another neuropsychological test : D2 test of attention	At the inclusion and at 12, 24 and 36 months	Study of remission rates frequency at 12 months depending on the D2 test (attention) assessed at baseline
scores to another other neuropsychological test : Rey-Osterrieth complex figure	At the inclusion and at 12, 24 and 36 months	Study of remission rates frequency at 12 months depending on the Rey figure assessed at baseline