To explore movement evoked pain in weight-bearing and non-weight-bearing activities in patients with chronic knee osteoarthritis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 41
- 试验地点
- 1
- 主要终点
- 2) Numeric Pain Rating Scale (NPRS) score in non-weight-bearing activities
研究概览
简要总结
After CTRI approval has been obtained, the participants will be screened based on the inclusion and exclusion criteria. They will be included in the study after giving their informed consent. Demographic details and knee osteoarthritis characteristics will be recorded, after which Knee Injury and Osteoarthritis Outcome Score (KOOS) and Michigan Body Map (MBM) will be administered. The participants will be asked to perform weight-bearing and non-weight-bearing activities, during which the movement evoked pain and its sensitivity will be recorded using the 11-point Numeric Rating Scale (NPRS). Quantitative sensory tests (QST)- temporal summation and pain pressure threshold will be assessed and the results will be recorded. Data will be analyzed statistically and the results will be reported.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 30.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •Chronic knee osteoarthritis (more than 3 months)
- •Conservatively managed or pre-operative knee osteoarthritis cases
- •Pain severity of more than 3 out of 10 on the Numeric Pain Rating Scale (NPRS)
- •Radiologically (Kellgren Lawrence grade of more than 0) or clinically (ACR criteria) diagnosed knee osteoarthritis
- •Can read and understand English and/or Kannada
- •Cognitively sound.
排除标准
- •Known case of neurological disorder (e.g., peripheral neuropathy, stroke, GBS, multiple sclerosis, spinal cord lesion, cognitive impairment)
- •Known case of systemic disorder (e.g., rheumatoid arthritis, SLE, fibromyalgia)
- •Skin lesion at assessment site
- •Pain for more than 3 months in areas other than the knee (e.g., chronic low back pain).
结局指标
主要结局
2) Numeric Pain Rating Scale (NPRS) score in non-weight-bearing activities
时间窗: One time assessment at the time of recruitment
3) Percentage change in pain severity in weight-bearing activities
时间窗: One time assessment at the time of recruitment
4) Percentage change in pain severity in non-weight-bearing activities
时间窗: One time assessment at the time of recruitment
1) Numeric Pain Rating Scale (NPRS) score in weight-bearing activities
时间窗: One time assessment at the time of recruitment
次要结局
- 1. Wind-up ratio(2. Pain pressure threshold)