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Study on the therapeutic effect and mechanism of massage on cognitive dysfunction after apoplexy

Phase 1
Recruiting
Conditions
stroke
Registration Number
ITMCTR2100004735
Lead Sponsor
Affiliated Hospital of Changchun University of Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1. Aged between 35-70 years;
2. Meet the diagnostic criteria for cerebral infarction, with head CT or MRI to identify the infarct focus;
3. Hamilton Depression Rating Scale (HAMD) <8 points;
4. The clinical dementia rating scale (CDR) score of all patients is 0.5 points;
5. Activity of Daily Living Ability Scale (ADL)> 60 points, basic self-care;
6. MMSE score is illiteracy >= 13 points, elementary school culture >= 19 points, middle school or above culture >= 24 points;
7. Total MoCA score < 26 for those with >= 12 years of education, < 25 for those with < 12 years of education, and refer to the baseline assumptions in the Expert Management Consensus on Cognitive Impairment after Stroke.

Exclusion Criteria

1. The course of cerebral infarction was less than 14 days or more than 6 months;
2. Family members complain of cognitive decline before cerebral infarction, or cognitive dysfunction caused by other reasons;
3. Patients with incomplete basic information and clinical data do not meet the scoring requirements of the scale;
4. Heart failure, Parkinson's disease, senile dementia, post-stroke dementia, cancer, critical disease, etc.;
5. Because of coma, mental disorders and other reasons and cannot cooperate with the patient;
6. Some diseases that interfere with the evaluation of cognitive function, including brain trauma and mental illness;
7. Patients who had taken drugs to improve cognitive function before screening.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Montreal Cognitive Assessment, MoCA;MRI;Mini-Mental State Examination, MMSE;
Secondary Outcome Measures
NameTimeMethod
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