The Effect of Endurance Training on Body Composition and Insulin Sensitivity in Prostate Cancer Patients Receiving Androgen Deprivation Therapy

Not Applicable

Completed

• Conditions: Prostate Cancer
• Interventions: Behavioral: Endurance training

• Registration Number: NCT01676480
• Lead Sponsor: Inge Holm

Brief Summary

The purpose of the present study is to investigate if endurance training can be used as a therapeutic action against the adverse metabolic disturbances and unfavourable changes in body composition that accompany the androgen deprivation therapy (ADT) treatment in prostate cancer patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-09
• Primary Completion: 2011-09
• Study Completion: 2011-09
• Study First Submitted: 2012-01-10
• Study First Submitted QC: 2012-08-28
• Study First Posted: 2012-08-31
• Status Verified: 2012-09
• Last Update Submitted: 2012-09-03
• Last Update Posted: 2012-09-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

• Prostate cancer patients receiving ADT for at least 3 months
• Healthy age and BMI matched controls

Exclusion Criteria

• severe cardiovascular disease
• severe arthritis
• severe neuropathy
• severe hypertension
• therapy with antidiabetic agents
• VO2max > 30.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
ADT group	Endurance training	-
Control group	Endurance training	-

Primary Outcome Measures

Name	Time	Method
Changes in body composition and insulin sensitivity in response to training	Body composition and insulin sensitivity are measured at baseline and after 12 weeks of endurance training

Trial Locations

Locations (1)

Centre of Inflammation and Metabolism, Rigshospitalet; 🇩🇰 Copenhagen, Denmark