The Effects of Red Spinach Extract Supplementation on Isometric Strength, Resistance Exercise and Cognitive Performance

Not Applicable

Completed

• Conditions: Sports
• Interventions: Dietary Supplement: Placebo; Dietary Supplement: Red Spinach Extract (RSE)

• Registration Number: NCT04292106
• Lead Sponsor: Lipscomb University

Brief Summary

Red Spinach is a natural food which is a rich source of nitrates, which are beneficial in hemodynamics, cardiovascular function, and have natural hypotensive and antianginal effects. Red spinach extract has been shown to be beneficial in exercise performance, albeit mostly in aerobic exercise. In a previous study in our lab, we found that dietary nitrate consumption resulted in significantly greater isometric force production in teenage males. However, currently there is little know regarding the effects of dietary nitrate supplementation on isometric strength, resistance exercise and cognitive performance.

Detailed Description

This research study is designed to measure the effects of red spinach extract (RSE) on markers of physical and cognitive performance during and following anaerobic exercise.

Study Timeline

• Study Start: 2019-09-26
• Study First Submitted: 2020-01-17
• Study First Submitted QC: 2020-02-28
• Study First Posted: 2020-03-02
• Primary Completion: 2020-03-30
• Study Completion: 2020-03-30
• Status Verified: 2022-01
• Last Update Submitted: 2022-01-13
• Last Update Posted: 2022-01-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 11

Inclusion Criteria

• 18-34 years old Participants must have at least 1 year of resistance training experience.
• Free of any physical limitations, medications, and supplements that may affect performance, as determined by a health and activity questionnaire.
• Are free of musculoskeletal injuries
• Are not taking medications that may interfere with study measurements

Exclusion Criteria

• Participants that cannot take either the RSE or placebo supplement will be excluded, as this will be a double-blind study.
• Furthermore, participants that cannot participate in pre- and post-research testing, and/or those that cannot commit to regular training sessions will be excluded.
• Inability to perform physical exercise (determined by health and activity questionnaire)
• Taking any other nutritional supplement or performance enhancing drug.
• Any chronic illness that causes continuous medical care

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Placebo	Placebo	-
Red Spinach Extract (RSE)	Red Spinach Extract (RSE)	-

Primary Outcome Measures

Name	Time	Method
Isometric Mid-thigh pull (IMTP) Peak Force	Through study completion, during both treatments (~4 weeks)	Peak Force will be measured via dual force plates during a full-body isometric strength test.
Isometric Mid-thigh pull (IMTP) Rate of Force Development	Through study completion, during both treatments (~4 weeks)	Rate of Force development will be measured via dual force plates during a full-body isometric strength test.
Bench Press Power	Through study completion, during both treatments (~4 weeks)	Power during bench press repetitions will be measured via a linear transducer.
Bench Press Repetitions to Fatiuge	Through study completion, during both treatments (~4 weeks)	Number of repetitions completed in each set during the acute exercise bout will be recorded and analyzed

Secondary Outcome Measures

Name	Time	Method
Cognitive Performance via Stroop Test	Through study completion, during both treatments (~4 weeks)	The Stroop Color and Word Test (SCWT) is a neuropsychological test used to assess cognitive performance. This will be administered before and after the fatiguing bench press protocol
Estimated Muscle Blood Flow via Near-infrared Spectroscopy (NIRS)	Through study completion, during both treatments (~4 weeks)	Measures of muscle oxygenation of the anterior deltoid will be estimated using a NIRS Device.

Trial Locations

Locations (1)

Jeremy Townsend; 🇺🇸 Nashville, Tennessee, United States