Continuation of Aspirin Before Isolated Heart Valve Surgery

• Conditions: Isolated Heart Valve Surgery
• Interventions: Drug: Aspirin

• Registration Number: NCT05151796
• Lead Sponsor: University of Liege

Brief Summary

Whether or not continuing aspirin up to de day before surgery increases the risk of bleeding and/or prevents thrombo-embolic complications remains debated. The investigators retrospectively investigated the whether continuing aspirine within 5 days of isolated heart valve surgery increased the risk of bleeding.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-05-01
• Primary Completion: 2017-05-01
• Study First Submitted: 2021-10-05
• Status Verified: 2021-11
• Study First Submitted QC: 2021-11-25
• Last Update Submitted: 2021-11-25
• Study Completion: 2021-12-01
• Study First Posted: 2021-12-09
• Last Update Posted: 2021-12-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

• Isolated heart valve surgery

Exclusion Criteria

• Antiplatelet agent other than aspirin or anticoagulant not discontinued preoperatively
• Emergent or salvage surgery
• Surgery for endocarditis
• Use of NSAIDs within 48 hours before surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Aspirin continued within 5 days before surgery	Aspirin	-

Primary Outcome Measures

Name	Time	Method
The number of units of packed red blood cells transfused anytime during the hospital stay	30 days

Secondary Outcome Measures

Name	Time	Method
Transfusion of any type of blood product	30 days
Chest tube drainage	24 hours	volume of chest tube drainage
Any thrombo-embolic complication	30 days
Surgical revision for bleeding	24 hours

Trial Locations

Locations (1)

CHU of Liege; 🇧🇪 Liège, Liege, Belgium