Platelet rich plasma transplantation with artificial bone graft material for sinus floor augmentatio

Phase 1

• Conditions: Atrophic maxillary alveolar bone

• Registration Number: JPRN-jRCTc030190274
• Lead Sponsor: Tobita Morikuni

Brief Summary

The safety of transplantation of a mixture of platelet-rich plasma and artifical bone replacement material during maxillary sinus floor elevation was evaluated,and a certain validity was confirmed.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-03-31
• Study Completion: 2021-10-20
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 2

Inclusion Criteria

1) Have missing tooth in the maxillary posterior region.
2) Require dental implant treatment at missing tooth site.
3) Require sinus floor augmentation (socket lift) at the dental implant placement.
4) Have good systemic condition.
5) Number of platelet is over 1x10E5 /microliter.
6) 20 years and older.
7) Other,the investigator believes makes him/her suitable for participation in this clinical study.

Exclusion Criteria

1) Have a history of Complicate malignant tumor.
2) Have an abnormal gingival proliferation or having a history of abnormal gingival proliferation.
3) Suspected of oral malignant tumor or precancerous lesion.
4) Under 20 years of old.
5) Have anti-coagulant or anti-platelet medications, or have a bleeding disorders.
6) Pregnancy, breastfeeding, or possibility of pregnancy.
7) Other,the investigator believes makes him/her unsuitable for participation in the clinical study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified