Platelet rich plasma transplantation for the intentional tooth replantatio

Phase 1

• Conditions: Fracture of dental root

• Registration Number: JPRN-jRCTc030190275
• Lead Sponsor: Tobita Morikuni

Brief Summary

The safety of transplantation of platelet-rich plasma at the replantation of teeth with fractured roots was evaluated,and a certain validity was confirmed.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-03-31
• Study Completion: 2022-09-24
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 2

Inclusion Criteria

1) Have a fracture of dental root.
2) Have a tooth which considered to effective by the tooth replantation.
3) Have good systemic condition.
4) Number of platelet is over 1x10E5 /microliter.
5) 20 years and older.
6) Other,the investigator believes makes him/her suitable for participation in this clinical study.

Exclusion Criteria

1) Have a separated dental root and have an abscess at the root apical.
2) Have a history of Complicate malignant tumor.
3) Have an abnormal gingival proliferation or having a history of abnormal gingival proliferation.
4) Suspected of oral malignant tumor or precancerous lesion.
5) Under 20 years of old.
6) Have anti-coagulant or anti-platelet medications, or have a bleeding disorders.
7) Pregnancy, breastfeeding, or possibility of pregnancy
8) Other,the investigator believes makes him/her unsuitable for participation in the clinical study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified