Research on brain function and epileptogenicity by spontaneous recording of electrocorticogram and single neuron activity

Not Applicable

Recruiting

• Conditions: epilepsy

• Registration Number: JPRN-jRCTs032190062
• Lead Sponsor: Shimada Seijiro

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-07-25
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1) Patients with epilepsy who meet any of the followings (1 drug resistance, 2 drug use difficulty due to side effects, 3 high expectancy of seizure freedom by surgery, which leads to significant benefit on social life)
2) Patients who undergo intracranial electrode placement for the purpose of epileptic focus localization and functional brain mapping
3) Patients who are 16 to 60 years old at the time of consent acquisition
4) Patients who signed the consent form by the patient's own free will after sufficient explanation and understanding on participating in this study
5) Gender does not matter

Exclusion Criteria

1) Patients with intellectual impairment and higher brain dysfunction (full scale IQ <60 by WAIS or WISC)
2) Patients whose participation in this study is judged as inappropriate by the principal investigator/subinvestigator

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Decoding accuracy of brain activity recorded by hybrid electrodes

Secondary Outcome Measures

Name	Time	Method
(1) Evaluation of temporal improvement of decoding accuracy by feedback of brain activity measured using hybrid electrodes<br>(2) Evaluation of an association between brain activity measured using a hybrid electrode and electroencephalographical indeces of epileptogenicity (ictal or interictal)<br>(3) Incidence of adverse events or related diseases