Towards defining abnormal musculoskeletal ultrasound findings * a study on hands and feet of healthy volunteers
- Conditions
- Normal variation of ultrasound10023213
- Registration Number
- NL-OMON46745
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 200
* Age * 18 years
* No previous prolonged and/or current symptoms of wrist, thumb base, metacarpal, interphalangeal and metatarsal joints
* Written informed consent
* No written informed consent
* Previous/current inflammatory joint disease (including crystal arthropathy).
* Visual analogue score (VAS) for current joint pain > 10/100.
* Any history of joint trauma in the last month.
* Fulfilling hand osteoarthritis according to the American College of Rheumatology clinical classification criteria.
* Any clinical joint inflammation, suggestive of inflammatory rheumatic disease, as identified by a physician.
* Previous or current inflammatory bowel disease.
* History of culture-proven enteric and/or genitourinary infection in the last month (assessed at history taking).
* Current or previous corticosteroids use in the last 4 weeks.
* Current non-steroidal anti-inflammatory drugs (NSAID) use (<7 days).
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The presence of inflammatory US features in joints and tendons of healthy<br /><br>subjects</p><br>
- Secondary Outcome Measures
Name Time Method <p>The presence of osteophytes detected by US in joints of healthy subjects.<br /><br>The relationship between the presence of inflammatory US features and<br /><br>osteophytes detected by US<br /><br>The relationship between the presence of inflammatory US features in healthy<br /><br>subjects and demographic characteristics (i.e. age, gender and body mass index)</p><br>