Giessen Pulmonary Hypertension in Lung Cancer Registry
- Conditions
- Pulmonary Hypertension Due to Lung Diseases and Hypoxia
- Interventions
- Other: All lung cancer patients.
- Registration Number
- NCT04467333
- Lead Sponsor
- University of Giessen
- Brief Summary
The aim of this study is to investigate the frequency and implications of pulmonary hypertension in lung cancer patients. To do so, data will be collected from all lung cancer patients at the university hospital Giessen. All data will be analyzed for possible hints of pulmonary hypertension as a comorbidity in lung cancer patients. All information will be generated from the regular guidelines based course of treatment and there will be no interventions. This study will serve as a prospective register for all lung cancer patients treated at the university hospital Giessen.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 500
- Patient with lung cancer at the University of Giessen lung Cancer Center.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description All lung cancer patients All lung cancer patients. There will not be an intervention.
- Primary Outcome Measures
Name Time Method sPAP values measured via Echocardiography. 2 years systolic pulmonary artery pressure (sPAP) measured in millimetre of mercury (mmHg).
Measurements of the pulmonary artery diameter (PA) and ascending aorta (AA) diameter measured via computed tomography scan. PA and AA will be measured in millimeters. 2 years PA and AA will be combined to report the PA/AA quotient as indicator for pulmonary hypertension in all lung cancer patients. With a cut off value of ≥ 1 defining pulmonary hypertension.
6 Minute Walk Test in meters. 2 years The 6 minute walk test is a sub-maximal exercise test used to assess aerobic capacity and endurance. The distance in meters covered over a time of 6 minutes is used as the outcome.
Modified Medical Research Council Scale (mMRC). 2 years Scores on the mMRC reach from 0-4, with higher scores indicating greater dyspnea.
chronic obstructive pulmonary disease assessment test (CAT). 2 years Scores on the CAT reach from 0-40, with higher scores indicating greater dyspnea.
Overall Survival and Progression Free Survival measured in days. 2 years Overall Survival and Progression free survival in days will be determined by Kaplan-Meier Analysis .Measuared in (st) (time from diagnosis to death)
Pulmonary function test measured via Spirometry. 2 years vital capacity, total lung capacity, forced expiratory volume in one second, functional vital capacity, diffusing capacity for carbon monoxide, arterial partial pressure of oxygen; all measured as % of predicted normal values.
Body mass index. 2 years weight and height will be combined to report BMI in kg/m\^2.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University hospital Giessen
🇩🇪Gießen, Hessen, Germany