Prospective Analysis of Natriuretic Peptides in Cardiac Surgery for the Prediction of Delirium and Postoperative Neurocognitive Deficits

• Conditions: F05.0; Delirium not superimposed on dementia, so described

• Registration Number: DRKS00011833
• Lead Sponsor: Klinikum der Ludwigs-Maximilians-Universität München, Campus Großhadern

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-03-03
• Study Completion: 2018-10-25
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

sceduled cardiac surgery with cardiopulmonary bypass

Exclusion Criteria

combined surgery, emergency surgery, chronic renal disease (GFR < 60 ml/min), liver cirrhosis with hepatic encephalopathy, preexistent psychiatric disease (dementia, schizophrenia, depression), pulmonary arterial hypertension, severe cognitive decline (MMSE < 24), preoperative hemoglobin level < 10g/dl

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Onset of delirium (Confusion Assessment Method for the Intensive Care Unit, Diagnostic and Statistical Manual of Mental Disorders 5th Edition, Chart-Based-Method within the hospital), POCD (Repeatable Battery for the Assessment of Neuropsychological Status preoperatively, at discharge and 6 months after discharge)

Secondary Outcome Measures

Name	Time	Method
risi factors, course of surgery and intensive care, sepsis, quality of life (Short Form-36 Health Survey), further parameters