Olfactory stimulation to improve the nutrition of premature infants

Not Applicable

Recruiting

• Conditions: P92.8; P07; Other feeding problems of newborn; Disorders related to short gestation and low birth weight, not elsewhere classified

• Registration Number: DRKS00023209
• Lead Sponsor: AG pädiatrische Olfaktologie Abteilung Neuropädiatrie Universitätsklinikum Dresden

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-02
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Premature infants from 25+0 SSW
- Premature infants up to 30+0 SSW
- Consent of the guardians to participate in the study
- Inclusion in the study before completion of the 48th hour of life
- Extubation before completed 48th hour of life

Exclusion Criteria

- Intubated beyond the 48th hour of life
- Intubation or re-tubation for more than 4 days after the start of the study
- complex heart defects
- Cerebral hemorrhages III°
- Orofacial malformations
- malformations of the central nervous system

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration until complete oral nutrition (independent drinking of all meals over 24 h) in days from birth

Secondary Outcome Measures

Name	Time	Method
Time to complete enteral nutrition (day of life with > 140 ml/kg/d of enteral feeds for 3 days) in days from birth, proportion of enteral feeds in total fluid on day 10, discharge weight and length of hospital stay, breastfeeding in the last 24 h before discharge, day of life on which 2/3 of total fluid (1/6 of bw) is consumed.