MedPath

Erector Spinae Plane Block With Bupivacaine for Medical Thoracoscopy

Phase 3
Terminated
Conditions
Postoperative Pain
Pleural Disease
Interventions
Drug: Placebo
Other: Monitored Anesthesia Care
Registration Number
NCT06313632
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Brief Summary

PlAcebo versus erector spINae pLane block for mEdical ThoracoScopy Study (PAINLESS). This is a prospective triple-blind, randomized controlled trial that evaluates the efficacy of erector spinae plane block (ESPB) with Bupivacaine in reducing pain after medical thoracoscopy (MT) in addition to monitored anesthesia care vs monitored anesthesia care alone.

Detailed Description

This is a single-site prospect triple-blind, randomized controlled trial, that evaluates the efficacy of erector spinae plane (ESP) block with Bupivacaine in reducing pain after medical thoracoscopy (MT). The study aims to compare the effectiveness of ESP block with monitored anesthesia care (MAC) vs MAC alone for patients undergoing MT. Patient will be evaluated post operatively in the post anesthesia care unit and 24 hours after the procedure.

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
33
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
ESP with PlaceboMonitored Anesthesia CareErector spinae plane injection with a placebo (normal saline).
ESP with PlaceboPlaceboErector spinae plane injection with a placebo (normal saline).
ESP with Bupivacaine GroupBupivacaine injectionErector spinae plane block with bupivacaine.
ESP with Bupivacaine GroupMonitored Anesthesia CareErector spinae plane block with bupivacaine.
Primary Outcome Measures
NameTimeMethod
Visual Analog Scale (VAS) for Pain2 hours after the intervention

Global chest pain score measured using the Visual Analog Scale (VAS) post-procedure in recovery. Participants will be asked to mark the level of their pain along a line, score ranges 0 (no-pain) to 100 (worst-imaginable pain), with higher scores indicating worse outcomes.

Secondary Outcome Measures
NameTimeMethod
Type of Analgesic usewithin the first 24 hours after the intervention

Type of Analgesic use within the first 24 hours after the intervention. The patient will be asked regarding the types of analgesics used (i.e. non-steroidal anti-inflammatories, opioids, etc.).

Change in the Numerical Rating ScaleAt 2 hours post-intervention and 24 hours post-intervention

Change in chest pain measured on the numerical rating scale post-procedure in recovery versus 24 hours post-procedure. This will be done using a numerical scale from 1 to 10 (1 = very mild pain, and 10 = very severe pain), with higher scores indicating greater levels pain. Data will be collected at the time of discharge from the recovery unit (2 hours post-intervention) vs 24 hours after.

Number of Analgesic usewithin the first 24 hours after the intervention

Number of Analgesics used within the first 24 hours after the intervention. The patient will be asked regarding number of doses.

Quality of Recovery-15 (QoR-15) Survey Scorewithin the first 24 hours after the intervention

Compare quality of recovery 24 hours after the intervention. This will be evaluated with the QoR-15 questionnaire, scores range Minimum: 0 to Maximum: 150, with higher scores indicating a better outcome and better quality of recovery.

Dosage of Analgesic usewithin the first 24 hours after the intervention

Dosage of Analgesic used within the first 24 hours after the intervention. The patient will be asked regarding dose used.

Trial Locations

Locations (1)

Mount Sinai West Hospital

🇺🇸

New York, New York, United States

© Copyright 2025. All Rights Reserved by MedPath