Ketanest in Intensive Care Unit Patients

Phase 4

Completed

• Conditions: intensive care patiënten waarbij inductie van anesthesie geïndiceerd is; coma; respiratory failure; 10024967

• Registration Number: NL-OMON35229
• Lead Sponsor: Canisius Wilhelmina Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Patients in an intensive care unit:
1. in need for ventilatory support.
2. to be intubated on the ICU.

Exclusion Criteria

1. <18 years old.
2. symptomatic coronary artery disease.
3. due to have surgery within 3 hours.
4. already on corticosteroid therapy
5. pregnancy.
6. pulmonary hypertension.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>CVP (10 min average)<br /><br>HR/BP (10 min average)<br /><br>MAP (10 min average)<br /><br>Urine output (60 min average)<br /><br>Resuscitation volume (specific sum)<br /><br>Inotropic support (value of rate and cumulative dose)<br /><br>Vasopressor support (value of rate and cumulative dose)<br /><br>Microcirculatory function</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Ventilatory and oxygen delivery variables<br /><br>Adverse psychological reactions</p><br>