The Influences of Malnutrition and Inflammation Complex Syndrome in Hemodialysis Patients

• Conditions: Inflammation; Hemodialysis; Malnutrition; Myocardial Ischemia; Cerebrovascular Accident

• Registration Number: NCT00190125
• Lead Sponsor: Far Eastern Memorial Hospital

Brief Summary

The purpose of this study is to explore the severity of malnutrition and inflammation in Taiwanese hemodialysis patients.

Detailed Description

Cardiovascular disease is the major of cause of mortality of hemodialysis patients. In addition to diabetes and hypertension, malnutrition and chronic inflammation are well-known to be major risk factors of cardiovascular diseases in normal population. For detecting the malnutrition and chronic inflammation and understanding the exact influences to hemodialysis patients, we conduct this study. We will collect the biochemical parameters, inflammatory markers, lipid parameters, hematologic parameters, and genomic DNA of patients. Then we will prospectively record the hospitalization, cardiovascular events, complications of arteriovenous fistula/graft, and mortality. According to the above results, we try to explore the exact role of malnutrition and inflammation in hemodialysis patients.

Study Timeline

• Status Verified: 2005-08
• Study First Submitted: 2005-09-11
• Study First Submitted QC: 2005-09-11
• Study First Posted: 2005-09-19
• Study Completion: 2007-08
• Last Update Submitted: 2009-02-06
• Last Update Posted: 2009-02-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Patients who have received hemodialysis therapy for more than three months

Exclusion Criteria

• Having active infection diseases now
• Patients who have a malignancy
• Had cardiovascular events in recent three months

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Far Eastern Memorial Hospital; 🇨🇳 Pan-Chiao, Taipei country, Taiwan